教师基本信息
姓名:沈侠
单位:粤港澳大湾区精准医学研究院(广州)
职称:研究员
邮箱:shenx@fudan.edu.cn
个人页面:http://www.ipm-gba.org.cn/Index/team_details/id/254.html
研究方向
统计遗传学
代表论文
1. Yang Z#, Macdonald-Dunlop E#, Chen J, Zhai R, Li T, Richmond A, Klaric L, Pirastu N, Ning Z, Zheng C, Wang Y, Huang T, He Y, Guo H, Ying K, Gustafsson S, Prins B, Ramisch A, Dermitzakis ET, Png G, Eriksson N, Haessler J, Hu X, Zanetti D, Boutin T, Hwang S-J, Wheeler E, Pietzner M, Raffield LM, Kalnapenkis A, Peters JE, Viñuela A, Gilly A, Elmståhl S, Dedoussis G, Petrie JR, Polašek O, Folkersen L, Chen Y, Yao C, Võsa U, Pairo-Castineira E, Clohisey S, Bretherick AD, Rawlik K, GenOMICC Consortium, IMI-DIRECT Consortium, Esko T, Enroth S, Johansson Å, Gyllensten U, Langenberg C, Levy D, Hayward C, Assimes TL, Kooperberg C, Manichaikul AW, Siegbahn A, Wallentin L, Lind L, Zeggini E, Schwenk JM, Butterworth AS, Michaëlsson K, Pawitan Y, Joshi PK, Baillie JK, Mälarstig A, Reiner AP, Wilson JF*, Shen X*. Genetic landscape of the ACE2 coronavirus receptor. Circulation. 2022; 145(18): 1398–1411.
2. Li T#, Ning Z, Yang Z, Zhai R, Xu W, Ying K, Wang Y, Chen Y, Shen X*. Total genetic contribution assessment across the human genome. Nature Communications. 2021; 12(1):2845.
3. Ning Z#, Pawitan Y, Shen X*. High-definition likelihood inference of genetic correlations across human complex traits. Nature Genetics. 2020; 52: 859–864.
4. Ning Z#, Lee Y, Joshi PK, Wilson JF, Pawitan Y, Shen X*. A selection operator for summary association statistics reveals allelic heterogeneity of complex traits. American Journal of Human Genetics. 2017; 101(6): 903-912.
5. Shen X#, Klarić L, Sharapov S, Mangino M, Ning Z, Wu D, Trbojević-Akmačić I, Pučić-Baković M, Rudan I, Polašek O, Hayward C, Spector TD, Wilson JF, Lauc G, Aulchenko YS*. Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation. Nature Communications. 2017; 8(1): 447.