教师基本信息

姓名：王冠琳

单位：复旦大学生命科学学院

职称：青年研究员

邮箱：guanlin_wang@fudan.edu.cn

个人页面：https://imib.fudan.edu.cn/af/14/c41546a438036/page.htm

研究方向

     单细胞多组学；分子进化；计算生物学

代表论文

      1. Wang Z#, Wu Z#, Wang H#, Feng R#, Wang G#,*, Li M#, Wang S#, Chen X#, Su Y, Wang J, Zhang W, Bao Y, Lan Z, Song Z, Wang Y, Luo X, Zhao L, Hou A, Gao H, Miao W, Liu Y, Wang H, Yin C, Ji Z, Feng M, Liu H, Diao L, Amit I, Chen Y, Zeng Y, Ginhoux F*, Wu X*, Zhu Y*, Li H*. An immune cell atlas reveals the dynamics of human macrophage specification during prenatal development. Cell, 2023 Sep 28;186: in press. (#co-first author, * corresponding author)

      2. Roy A#.*, Wang G#, Iskander D, O’Byrne S, Elliott N, O’Sullivan J, Buck G, Heuston EF, Wen WX, Meira AR, Hua P, Karadimitris A, Mead AJ, Bodine DM, Roberts I, Psaila B*, Thongjuea S*. Transitions in lineage specification and gene regulatory networks in hematopoietic stem/progenitor cells over human development. Cell Reports. 2021 Sep 14;36(11). (#co-first author)

      3. Psaila B#,*, Wang G#, Rodriguez-Meira A, Li R, Heuston EF, Murphy L, Yee D, Hitchcock IS, Sousos N, O’Sullivan J, Anderson S, Senis YA, Weinberg OK, Calicchio ML, Iskander D, Royston D, Milojkovic D, Roberts I, Bodine DM, Thongjuea S*, Mead AJ*. Single-cell analyses reveal megakaryocyte-biased hematopoiesis in myelofibrosis and identify mutant clone-specific targets. Mol Cell. 2020 May 7;78(3):477-492.e8. (#co-first author)

      4. Wang G, Li B, Zhang X, Niu C, Li J, Li L, Speakman JR. No seasonal variation in physical activity of Han Chinese living in Beijing. Int J Behav Nutr Phys Act. 2017 Dec;14:1-10.

      5. Wang G, Speakman JR*. Analysis of positive selection at single nucleotide polymorphisms associated with body mass index does not support the “thrifty gene” hypothesis. Cell Metab. 2016 Oct 11;24(4):531-541.